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Citrulline Malate is a powerful amino acid compound that plays a crucial role in boosting nitric oxide production, enhancing endurance, improving blood flow, and reducing muscle fatigue. It is formed by combining L-Citrulline, a non-essential amino acid, with malic acid, which aids in energy production through the Krebs cycle.
By increasing nitric oxide levels, Citrulline Malate widens blood vessels, enhances oxygen and nutrient delivery to muscles, and helps remove ammonia buildup, reducing fatigue and improving recovery. This makes it an essential supplement for athletes, bodybuilders, and anyone looking to maximize their workouts.
That being said, our team at Generation Iron has tried, tested and compiled a list of the best citrulline malate supplements for 2025. Let’s dive in.
The Best Citrulline Malate Supplements of 2025
- Best Citrulline Overall: Nutricost L-Citrulline Malate
- Pre-Workout for Citrulline: Transparent LABS BULK
- Best Citrulline for Nitric Oxide Production: Transparent Labs Lean Pre-workout
- Best Citrulline Pills: Nutricost L-Citrulline
- Best Citrulline for Vegans: Nutricost L-Citrulline Malate
Best Citrulline Supplement Overall: Nutricost L-Citrulline Malate
If you’re looking for pure, high-quality citrulline without any additives, Nutricost L-Citrulline is the top choice. Unlike citrulline malate, this supplement contains only L-Citrulline base powder, ensuring you receive the essential amino acid without additional compounds.
- Key Benefits:
- 600 grams of pure L-Citrulline powder per container
- 3 grams per serving
- 200 servings per container
- Non-GMO and gluten-free
- Manufactured in a GMP-compliant, FDA-registered facility
This supplement is ideal for those looking to maximize muscle endurance, improve blood flow, and support recovery without unnecessary fillers.
Best Pre-Workout With Citrulline: Transparent Labs BULK
Transparent Labs PreSeries BULK is backed by science with clinically effective dosages to increase muscle size and mass. This pre-workout is perfect for reducing fatigue, aiding in muscle growth, and boosting energy levels for better overall performance.
For those who prefer their citrulline malate in a high-performance pre-workout, Transparent Labs BULK is unbeatable. This pre-workout supplement is packed with key ingredients that boost workouts, improve endurance, and support muscle growth.
- Key Ingredients Per Serving:
- 6,000 mg of Citrulline Malate
- 4,000 mg of Beta-Alanine
- 4,000 mg of BCAAs
- 2,500 mg of Betaine
- Vegan-friendly formula
Transparent Labs BULK is designed to improve performance, blood flow, and recovery, while also aiding in weight loss and muscle growth. If you’re looking for a clean pre-workout with a powerful nitric oxide boost, this is the one to get.
Best Citrulline for Nitric Oxide: Transparent Labs PreSeries LEAN
Transparent Labs PreSeries LEAN is perfect for those looking to target stubborn belly fat while still maintaining that hard-earned lean muscle. For those looking to slim down and lose weight, look no further than this great pre-workout with quality ingredients at effective dosages.
If your main goal is to enhance nitric oxide production for better blood flow and endurance, Transparent Labs PreSeries LEAN is the best citrulline malate supplement for the job.
- Key Features:
- Designed for fat loss and high-intensity training
- 21 active ingredients
- No artificial dyes, fillers, or harmful additives
- Vegan-friendly and sugar-free (sweetened with stevia)
This pre-workout is perfect for those who want to boost nitric oxide levels while maintaining a lean physique. With natural flavors and high-quality ingredients, PreSeries LEAN delivers a great workout experience without the unnecessary extras.
Best Citrulline Pills: Nutricost L-Citrulline Pills
For those who prefer capsules over powders, Nutricost L-Citrulline Pills provide an easy and effective way to get your daily dose of citrulline.
- Key Benefits:
- 2.5 grams (2,500 mg) of L-Citrulline per serving
- 60 servings per bottle (120 tablets)
- Third-party tested for quality and safety
- Manufactured in a GMP-compliant, FDA-registered facility
- Non-GMO and gluten-free
Nutricost’s L-Citrulline tablets are a convenient option for those who want the benefits of citrulline without mixing powders.
Best Vegan Citrulline Malate: Nutricost Citrulline Malate
Vegans looking for a high-quality citrulline supplement will appreciate Nutricost Citrulline Malate. This supplement provides all the benefits of citrulline malate in a formula that meets vegan standards.
- Why It Stands Out:
- Vegan-friendly formula
- Supports muscle endurance and nitric oxide production
- Manufactured with high-quality ingredients
This supplement is ideal for plant-based athletes who want to improve their performance with a clean, effective formula.
How We Choose
Our team at Generation Iron tests numerous products to really narrow down our lists, whether that be equipment, supplements, or something else. With over a decade in the fitness industry, our team of experts knows exactly what to look for, so we can make sure our word is good.
Best Citrulline Supplements Final Thoughts
Citrulline Malate is a powerful ingredient that can boost nitric oxide production, improve endurance, and enhance blood flow. By supporting better oxygen delivery and faster muscle recovery, it is a must-have for those looking to optimize their training.Whether you prefer a pure citrulline powder, a pre-workout formula, or the convenience of tablets, the options listed above represent the best citrulline supplements on the market. Choose the one that fits your fitness goals and experience the performance benefits today!
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