Best Joint Supplements For Inflammation & Joint Health (Updated 2021)

joint supplements

The best joint supplements help to reduce inflammation and provide the necessary nutrients for joint health.

When choosing a joint supplement, it is important to look at both the ingredients and filler ingredients. Our list covers joint supplements for athletes, best joint supplements for men, and the best joint supplements for women. Joint supplements are one of the more effective supplements you can spend your money on. And getting a good one can make a big and very quick difference to not just an athlete’s performance, but the day to day life of all men and women.

In fact, you don’t even need to have joint issues like arthritis or an injury to benefit from a joint supplement. They can promote fluid movement and support people like bodybuilders who put masses of strain on their joints, or runners looking to protect their knees. Choosing the best joint supplement comes down to one thing, the formula. Here’s our top joint supplements.

Best Joint Supplement For Bodybuilders Overview

As bodybuilders, we know how much our bodies can take. Pushing ourselves to the limit and seeking that perfect symmetry can take its toll and we notice that. Our joints are those prime movers, those valuable points of contact that allow us to lift as much weight as we want. But when those get sore, or worse, strained or injured, it leaves us out of the gym doing what we love. The right joint supplement can keep our joints as healthy as possible so we don’t have to deal with any of that. And it will ultimately keep us as healthy as possible overall.

We’ve put together a list of the Best Joint Supplements for 2021 so you have the best chance at staying safe and healthy in the gym while operating at fully capacity with the best movements.

Best Joint Supplements For 2021

Best Overall Joint Supplement

Offering a fully stacked formula of proven joint protection ingredients, Physio Flex Pro is actually verified and approved by a physical therapist. It’s combination and balanced approach means that it easily takes top spot when it comes to the best joint supplements and best joint supplements for athletes.

Physio Flex Pro

Number Of Ingredients 8
Serving Size 2 Capsules
Number of Servings 30
Best Way To Take Take 2 capsules with your desired beverage of choice.

Physio Flex Pro can help restore and even strengthen joints in athletes, bodybuilders and people experiencing age related joint issues. By reducing inflammation with turmeric, Bromelain and ginger root, you’ll find you can move pain and crack-free. Then with Glucosamine, Chondroitin and MSM supporting healthy cartilage and synovial fluid, motion will become more ‘free’ and you’ll feel less restricted. Physio Flex Pro offers a complete and ‘total joint support’ which we found the absolute best in terms of doses, effects and end results of supplementation.

Physio Flex Pro is a research-based joint support supplement made with natural ingredients great for nourishing and lubricating your joints.


  • Fast effects
  • Elite level formulation with high doses
  • Backed by a physical therapist
  • Natural easy to digest ingredients
  • Affordable monthly cost with bundles
  • Created by working athletes


  • Only available online
  • $15 tracked shipping on international orders

Price: $60.00

Check out our individual review for Physio Flex Pro here!

Best Joint Supplement For Joint Lubrication

The best joint supplement for joint lubrication will keep your joints moving effortlessly without any uncomfortable grinding or stuck feeling. With so many movements taking such a toll on our joints, having a supplement like Performance Lab Flex can greatly benefit all your gains.

Performance Lab Flex

Number Of Ingredients 6
Serving Size 2 NutriCaps
Number of Servings 30
Best Way To Take Take 2 capsules daily.

Performance Lab Flex is joint support product that optimizes your joints and mobility for long term enhanced flexibility, comfort, and performance. It uses a similar formula to Physio Flex Pro but uses ‘branded’ ingredients. It’s a solid product and will work well for those looking to purchase their joint supplement alongside other supplements. Great for joint lubrication and shock absorption, this will support your ligaments, tendons, and cartilage with herbal relief for those stuff joints.

Performance Lab Flex is perfect for joint lubrication and shock absorption that provides herbal relief for stiff and achy joints.


  • Great benefits like joint lubrication and shock absorption
  • Easy to swallow prebiotic NutriCaps
  • 100% clean and natural product
  • From a reputable company in Performance Lab


  • Premium priced option
  • Only available directly from their website

Price: $69.00

Check out our individual review for Performance Lab Flex here!

Best Joint Supplement For Inflammation

Inflammation and muscle soreness can be a real pain. When it comes to our joints, that can really hinder our training and performance, as well as everyday movements. Thankfully, Transparent Labs has created a great joint support supplement perfect for fighting unwanted inflammation.

Transparent Labs WellnessSeries Joint Support

Number Of Ingredients 5
Serving Size 2 Capsules
Number of Servings 30
Best Way To Take Take 2 capsules daily with 8 oz. of water.

WellnessSeries Joint Support offers a great joint support formula that differs from others on the market. While many contain unproven ingredients like glucosamine and chondroitin, Transparent Labs has built this comprehensive joint supplement from five clinically studied ingredients. You can find comfort knowing there are zero artificial sweeteners, coloring, or preservatives and that this product is gluten-free and non-GMO to give you the best quality ingredients around. With patented doses of well-researched ingredients, this supplement will promote healthy joint integrity, fight oxidative stress, and decrease inflammation to keep you moving efficiently.

Transparent Labs WellnessSeries Joint Support is perfect for promoting joint integrity, fighting oxidative stress, and decreasing inflammation with well-researched ingredients and a transparent label.


  • Great for fighting inflammation and oxidative stress
  • Thoroughly tested and clean ingredients
  • 100% transparent formula and label
  • From a reputable company in Transparent Labs


  • Premium priced option
  • Only available directly from their website

Price: $49.00

Use the promo code GENIRON10 for 10% off! Also, check out our individual for Transparent Labs Joint Support here!

deadlift alternatives

Why Do Bodybuilders Need Joint Supplements?

As we will discuss further below in the benefits section, joint supplements can greatly affect your bodybuilding training and performance by alleviating unwanted pain and offering the best support for your joints. Keeping them lubricated and moving properly will affect how you move and how hard you can push yourself. With the right supplement, this will prioritize your physical health over all else. With the constant wear and tear of our workouts, the right joint supplement will be incredibly beneficial for all your gains.

Best Ingredients in Joint Supplements

The best ingredients in joint supplements are always natural. These ingredients are aimed to reduce inflammation, lubricate joints, and replenish the body with vitamins and minerals. Below we’ve selected ingredients that are supported by scientific studies to ensure they work as they should.

Some of these ingredients may be hard to pronounce but they offer great benefits for people with joint pain. This is because they have properties that help increase mobility, decrease stiffness, and more.


Glucosamine is a supplement that is used for joint health (1). It helps with cartilage formation and repair by providing a protein building block called glucosamine that the human body cannot produce on its own.

Glucosamine supplements have been shown to have three major benefits:

  • They reduce the frequency of pain and morning stiffness.
  • They increase mobility in the joints.
  • They improve function of the joints.


Turmeric is a natural anti-inflammatory and antioxidant that has been used as a remedy for joint pain, arthritis, and other related conditions for centuries.

Turmeric’s health benefits stem from curcumin, an antioxidant and anti-inflammatory ingredient that has been linked to such conditions as arthritis, inflammatory bowel disease (IBD), ulcerative colitis (UC) and Crohn’s disease (2).


MSM is an organic sulfur-containing compound that contains no toxic metals. It is also known as dimethyl sulfone (DMSO2).

MSM contains sulfur which helps to form the healthy, hydrated tissues in our body.

MSM can help with joint pain and arthritic pain by helping with inflammation and repair of tissues in the joints.


Boswellia is a natural anti-inflammatory agent which relieves pain and inflammation of the joints. Boswellia has been used for thousands of years to treat a variety of illnesses, including arthritis and asthma (3).

Boswellia can be used in many ways: in its raw form, as an extract or as a cream that may help reduce muscle stiffness and discomfort.

Ginger Root

Ginger Root is a plant that grows in certain parts of the world. Many people use it to provide joint protection by taking it as a supplement or putting it into their cooking.

There are many benefits that come with Ginger Root including pain relief, inflammation reduction, and general health benefits. This plant is really good for the body and can help prevent some serious health problems like arthritis (4).

Many of the Ginger Root benefits are because of its ability to block an enzyme that causes inflammation called COX-2. This enzyme is responsible for causing things like nausea and vomiting during pregnancy (morning sickness), inflammation reduction, and pain relief.


Collagen is an essential protein that’s found in the body. It provides structure and strength to tissues throughout the body including the skin, hair, nails, muscles, bones, tendons, and ligaments (5).

Collagen helps to protect joints by providing a cushioning effect on the cartilage. It also helps to lubricate joints during movement. Collagen can be used for joint protection because it may help to maintain healthy joints and promote healthy cartilage levels.


Chondroitin is a natural substance that is found in the cartilage of the body. Chondroitin makes up about 10 to 30% of the total protein content in cartilage.

Chondroitin’s health benefits are not limited to joint pain control, but also for other benefits like improved mobility, increased production of synovial fluid, and improved blood flow (6).

strong man

Benefits of Joint Supplements

Our best joint supplements are dietary supplements that contains ingredients believed to promote joint health. Joint supplements often contain glucosamine, chondroitin, and other substances. There are many benefits of joint supplements which you can find on this section.

  • Restore Strength and Mobility

Joint supplements can help nourish and strengthen key joints in the body. They do this by providing nutritional ingredients like Glucosamine, Chondroitin and MSM which can be digested and used to improve key structures of the joint and musculoskeletal systems in the body. This means less aching joints and more moving.

  • Help with Fluid Movement

By nourishing the joints, most good joint supplements also impact synovial fluids. This means that you’re essentially lubricating your joints, allowing for free flowing and fluid movements.

  • Reduce Inflammation

A joint supplement should also reduce inflammation and swelling of joints. This can hugely help remove discomfort and improve quality of life. Inflamed joints can occur for a variety of reasons too, so taking a joint supplement can offer protection against this problem.

  • Reduce Pain

Joint pain is a huge issue globally and can be severely debilitating for people looking to live an active life. The ingredients in an effective joint supplement can help reduce painful joints by targeting inflammation and improving strength.

  • Improve Lifestyle

An obvious one, but by fixing up your joints, your quality of life will shoot up. We always check to see if our best joint supplements will help you live a fuller and more active and free lifestyle. Our best joint supplements for athletes will ensure you are performing at your peak.

fat burners belly fat muscle maintenance weight loss energy boost muscle breakdown

How to Find the Best Joint Supplement

Joint supplements are necessary for all people who want to keep their joints in perfect shape and health. Even though there are many joint supplements available on the market, it can be hard to choose the right one.

So how do you know if a joint supplement is worth buying or even the best joint supplement for you?

There are many things that you should know before buying a supplement. Firstly, you need to know the ingredients that are used in the supplement because these ingredients are what make it work or not work for your joints. Some people also prefer getting their supplements from natural sources because they don’t contain any artificial chemicals or preservatives which could harm their body.

How We Choose

When it comes to finding the right joint supplements, we first look at the brand and its reputation. You deserve to have a company working on your behalf with only the best products. We then look at ingredients and effectiveness. It’s important you only put the best ingredients in your body that are also effective to keep you and your joints healthy overall. Finally, we look at price. Supplements can get expensive but it is possible to find the right products at affordable prices.

strong man

FAQ Section

What is the best joint supplement?

Physio Flex Pro. This can help restore and even strengthen joints in athletes, bodybuilders and people experiencing age related joint issues. By reducing inflammation with turmeric, Bromelain and ginger root, you’ll find you can move pain and crack free.

Do joint supplements actually work?

The right joint supplement with proper ingredients will work wonders for you. There are some shady companies always looking to make a buck before prioritizing your health but this list above contains great supplements from reputable and honest companies.

Are joint supplements safe to take?

On the whole, joint supplements are safe to take. However, like all supplements, it is important to read the label and make sure all ingredients are suitable for you to take. Any other questions, it is smart to reach out to an expert for further advice.

Wrap Up

Joint supplements can greatly affect your joint health and keep you moving efficiently inside and out of the gym. With the right products, you are well on your way to continued gains without the fear of pain or injury. These joint supplements are perfect for helping all your goals and can offer great benefits while being worthy of you taking. Give these a try and work to stay as healthy as possible inside and out of the gym.

Generation Iron may receive commissions on purchases made through our links. See our disclosure page for more information.

Let us know what you think in the comments below. Also, be sure to follow Generation Iron on Facebook, Twitter, and Instagram. 

*Images courtesy of Envato


  1. National Institute of Health: National Center for Complementary and Integrative Health. “Glucosamine and Chondroitin for Osteoarthritis”. (source)
  2. Daily, J.; et al. (2016). “Efficacy of Turmeric Extracts and Curcumin for Alleviating the Symptoms of Joint Arthritis: A Systematic Review and Meta-Analysis of Randomized Clinical Trials”. (source)
  3. Yu, G.; et al. (2020). “Effectiveness of Boswellia and Boswellia extract for osteoarthritis patients: a systematic review and meta-analysis”. (source)
  4. Mashhadi, N. (2013). “Anti-Oxidative and Anti-Inflammatory Effects of Ginger in Health and Physical Activity: Review of Current Evidence”. (source)
  5. Moskowitz, R. (2000). “Role of collagen hydrolysate in bone and joint disease”. (source)
  6. Henrotin, Y.; et al. (2014). “What is the current status of chondroitin sulfate and glucosamine for the treatment of knee osteoarthritis?”. (source)
Austin Letorney is a writer, actor, and fitness enthusiast. As a former rower, he has shifted his focus to sharing his knowledge of the fitness world and strength sports with others.